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Ecdysterone promotes lean mass gains via estrogen receptor-beta (ERβ) activation.

This is noteworthy since ERβ signaling is involved in the regulation of skeletal muscle growth and regeneration by stimulating anabolic pathways, activating satellite cells, and modulating immune function.

Furthermore, ecdysterone has also been suggested to support muscle protein synthesis via direct or indirect stimulation of the PI3K/Akt signaling pathway.

Most importantly, ecdysterone does NOT interact with the androgen receptor, meaning it will not cause suppression or any other unwanted side effects commonly found with AAS usage. (From advanced muscle labs)

Capsaicin binds TRPV1 receptors in the body, manifesting some of the anti-inflammatory effects, will promote increased blood flow and some mild heat production.

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